Product Name: Anastrozole
Active Ingredient:
Anastrozole
Description:
Anastrozole is a potent, non-steroidal aromatase inhibitor used primarily in the treatment of hormone receptor-positive breast cancer in postmenopausal women. It works by inhibiting the aromatase enzyme, which is responsible for the conversion of androgens to estrogens in the body. By lowering estrogen levels, anastrozole helps reduce the growth of estrogen-dependent breast cancer cells. Anastrozole is considered an effective treatment for both adjuvant therapy and metastatic breast cancer.
Quantitative and Qualitative Composition:
- Active Substance: Each tablet contains 1 mg of anastrozole.
- Excipients: Cellulose, magnesium stearate.
Pharmaceutical Form:
White, circular tablets for oral administration.
Packaging:
40 tablets per container.
Pharmacotherapeutic Classification:
Aromatase inhibitors (ATC Code: L02BG03)
Therapeutic Indications:
- Breast Cancer Treatment: Anastrozole is indicated for the adjuvant treatment of hormone receptor-positive breast cancer in postmenopausal women. It is used to reduce the risk of recurrence following surgery and radiation therapy.
- Metastatic Breast Cancer: Anastrozole is also used in the treatment of metastatic breast cancer in postmenopausal women whose disease is estrogen receptor-positive.
- Breast Cancer Prevention: In some high-risk populations, anastrozole may be used off-label for the prevention of breast cancer in postmenopausal women.
- Ovarian Cancer: Anastrozole has also been investigated in clinical trials for use in the treatment of ovarian cancer, particularly in women with hormone receptor-positive tumors.
Dosage and Administration:
Anastrozole is typically administered orally, with a standard dosage of 1 mg once daily. The dosage may be adjusted based on clinical response, and treatment duration is determined by the healthcare provider. For metastatic breast cancer, anastrozole is generally continued until disease progression or unacceptable toxicity occurs.
Storage Conditions:
Store below 25°C. Protect from moisture and light. Keep out of reach of children.
Regulatory Status:
Prescription-only medication (Rx).
Manufactured in accordance with current Good Manufacturing Practice (cGMP) standards.